Afwan, Fida' Mushalim and , dr. Retno Sintowati, M.Sc (2018) Uji Efek Hepatoprotektor Propolis Madu Alam Khas Kalimantan Terhadap Kerusakan Struktur Morfologi Sel Hepar Mencit Jantan(Mus musculus, L.) yang Diberi Paparan Asap Rokok. Skripsi thesis, Universitas Muhammadiyah Surakarta.
![[img]](http://eprints.ums.ac.id/style/images/fileicons/application_pdf.png) |
PDF (Naskah Publikasi)
NASKAH PUBLIKASI.pdf Download (406kB) |
|
PDF (Halaman Depan)
HALAMAN DEPAN-206.pdf Download (579kB) |
|
PDF (Bab I)
BAB I.pdf Download (2MB) |
|
PDF (Bab II)
BAB 2.pdf Restricted to Repository staff only Download (2MB) |
|
PDF (Bab III)
BAB 3.pdf Restricted to Repository staff only Download (2MB) |
|
PDF (Bab IV)
BAB 4.pdf Restricted to Repository staff only Download (2MB) |
|
PDF (Bab V)
BAB 5.pdf Restricted to Repository staff only Download (2MB) |
|
PDF (Daftar Pustaka)
DAFTAR PUSTAKA.pdf Download (2MB) |
|
PDF (Lampiran)
LAMPIRAN.pdf Restricted to Repository staff only Download (2MB) |
|
PDF (Surat Pernyataan Publikasi Ilmiah)
SURAT PERNYATAAN PUBLIKASI KARYA ILMIAH.PDF Restricted to Repository staff only Download (74kB) |
Abstract
Background: Propolis is a resin collected by bees from various plants, which mix with saliva and various enzymes to produce different new resins. Propolis has antibacterial, antikapang, antiviral and other biological activities such as anti-inflammatory, local anesthesia, hepatoprotector, antitumor, and immunostimulant. Purpose: To determine the ability of natural propolis hepatoprotector typical of Kalimantan to damage morphological structure of male mice liver (Mus musculus, L.) exposed to cigarette smoke. Method: This study used an experimental research design with complete randomized design (post randomized design) posttest only with control group design. The subjects used were 30 male mice (Mus musculus, L) Swiss Webster strain aged ± 3 months with weight 20-30 grams. Ethanol propolis extract with a dose of 0.1 ml treatment; 0.2 ml; 0.4 ml; tested the effect of hepatoprotector on the morphological structure of male mice liver cells (Mus musculus L). With the number of 6 mices, divided into 5 groups of the normal control group (aquadest), negative control (1 cigarette), treatment 1 (1 cigarette + 0.1 ml propolis extract), treatments 2 (1 cigarette + propolis extract 0.2 ml) and treatments 3 (1 cigarette + 0.4 ml propolis extract). Then made preparations, observed and calculated morphological damage to liver cell based on cell damage criteria (pyknosis, karyorhexis, and karyolisis). Research data were analyzed statistically by using statistical application in computer. Result: Ethanol propolis extract of natural honey typical of Kalimantan effectively inhibit the damage of morphological structure of male mice liver (Mus musculus, L.) exposed to cigarette smoke with a dose of 0.1 ml; 0.2 ml; 0.4 ml treatment. Conclusion: Ethanol propolis extract of natural honey typical of Kalimantan with a dose of 0.1 ml; 0.2 ml; 0.4 ml treatment effectively inhibits damage to the morphological structure of male mice liver cells (Mus musculus, L.) exposed to cigarette smoke.
| Item Type: | Karya ilmiah (Skripsi) |
|---|---|
| Uncontrolled Keywords: | Propolis, Hepatoprotektor, Cigarette smoke, Mus musculus L |
| Subjects: | R Medicine > R Medicine (General) |
| Divisions: | Fakultas Kedokteran > Kedokteran |
| Depositing User: | FIDA' MUSHALIM AFWAN |
| Date Deposited: | 06 Feb 2018 02:29 |
| Last Modified: | 06 Feb 2018 02:29 |
| URI: | http://eprints.ums.ac.id/id/eprint/59282 |
Actions (login required)
 |
View Item |
