Pengaruh Pemberian Ekstrak Bunga Mawar Merah (Rosa Damascena Mill.) Terhadap Morfologi Sel Ginjal Pada Tikus Putih Galur Wistar (Rattus Norvegicus) Yang Diinduksi Karbon Tetraklorida (CCl4).

Amdat, Muhammad Khozaainul Saddam and , Dr. Retno Sintowati, M.Sc. and , Riandini Aisyah, S.Si, M.Sc (2017) Pengaruh Pemberian Ekstrak Bunga Mawar Merah (Rosa Damascena Mill.) Terhadap Morfologi Sel Ginjal Pada Tikus Putih Galur Wistar (Rattus Norvegicus) Yang Diinduksi Karbon Tetraklorida (CCl4). Skripsi thesis, Universitas Muhammadiyah Surakarta.

	PDF (Naskah Publikasi) NASKAH PUBLIKASI-libraryums-khozaainul.pdf Download (1MB)
	PDF (HALAMAN DEPAN) HALAMAN DEPAN.pdf Download (4MB)
	PDF (BAB 1) BAB 1.pdf Download (184kB)
	PDF (BAB 2) BAB 2.pdf Restricted to Repository staff only Download (303kB) | Request a copy
	PDF (BAB 3) BAB 3.pdf Restricted to Repository staff only Download (424kB) | Request a copy
	PDF (BAB 4) BAB 4.pdf Restricted to Repository staff only Download (377kB) | Request a copy
	PDF (BAB 5) BAB 5.pdf Restricted to Repository staff only Download (147kB) | Request a copy
	PDF (DAFTAR PUSTAKA) DAFTAR PUSTAKA.pdf Download (178kB)
	PDF (LAMPIRAN) LAMPIRAN.pdf Restricted to Repository staff only Download (1MB) | Request a copy
	PDF (PERNYATAAN) pernyataan naspub.pdf Restricted to Repository staff only Download (861kB) | Request a copy

Abstract

Background: Tetrachloride Carbon (CCl4) is subtance that can trigger free radicals. Free radicals formed as aerobic metabolism’s normal result, but they can increase at pathological conditions, because there is an imbalance between the free radicals by the body’s natural antioxidant. CCl4 causes Acute Tubular Necrosis with the pathologydescriotion in the kidney. Red rose (Rosa damascena Mill.) contains antioxidant. Purpose: to find out the effect of red rose extract (Rosa damascena Mill.) on kidney cell morphology of Galur Wistar Mice (Rattus norvegicus) induced with Tetrachloride Carbon (CCl4). Method: Mice were divide in 5 groups, each 5 mice were treat in different treatments, that are in negative control, in positive control (induced CCl4), P1 (induced CCl4 and red rose extract 250mg), P2 (induced CCl4 and red rose extract 500mg), P3 (induced CCl4 and red rose extract 1000mg). CCl4 was given subcutaneousty in every 7 days and red rose extract was given orally every day during 14 days. After that mice were dissected, their kidneys were made as histology preparation by HE colouring. The result was processed by using One Way Anova test. Result: The result of Kruskal Wallis test on red rose extract shows the total scores of yhe right kidney cell damage is p=0,000. As score (p<0,05), so there is a significant difference. Conclusion: By giving red rose extract in I, II, and III (250mg, 500mg, and 1000mg) during 14 days can repair the morfologi glomerulus cell in damage of Wistar Mice’s kidney induced withTetrachloride Carbon (CCl4). Keywords: Red Rose, CCl4, Morfologi, Antioxidant

Item Type:	Karya ilmiah (Skripsi)
Uncontrolled Keywords:	Mawar Merah,CCl4, Morfologi, Antioksidan
Subjects:	R Medicine > RB Pathology R Medicine > RM Therapeutics. Pharmacology
Divisions:	Fakultas Kedokteran > Kedokteran
Depositing User:	MUHAMMAD KHOZAAINUL SADDAM AMDAT
Date Deposited:	15 Aug 2017 06:41
Last Modified:	15 Aug 2017 06:41
URI:	http://eprints.ums.ac.id/id/eprint/52618

Actions (login required)

View Item