Uji Aktivitas Antiinflamasi Ekstrak Etanol Rimpang Lengkuas (Alpinia Galanga) Pada Tikus Putih Jantan Galur Wistar Yang Diinduksi Karagenin

Sari, Intan Arsyita and , Arifah Sri Wahyuni, M.Sc.,Apt. (2018) Uji Aktivitas Antiinflamasi Ekstrak Etanol Rimpang Lengkuas (Alpinia Galanga) Pada Tikus Putih Jantan Galur Wistar Yang Diinduksi Karagenin. Skripsi thesis, Universitas Muhammadiyah Surakarta.

	PDF (Halaman Depan) HALAMAN DEPAN_1.pdf Download (980kB)
	PDF (Bab I) BAB I_1.pdf Download (166kB)
	PDF (Bab II) BAB II_1.pdf Restricted to Repository staff only Download (154kB) | Request a copy
	PDF (Bab III) BAB III_1.pdf Restricted to Repository staff only Download (426kB) | Request a copy
	PDF (Bab IV) BAB IV_1.pdf Restricted to Repository staff only Download (6kB) | Request a copy
	PDF (Daftar Pustaka) DAFTAR PUSTAKA_1.pdf Download (240kB)
	PDF (Lampiran) LAMPIRAN_1.pdf Restricted to Repository staff only Download (1MB) | Request a copy
	PDF (Pernyataan Publikasi Ilmiah) Pernyataan publikasi.pdf Restricted to Repository staff only Download (311kB) | Request a copy
	PDF (Naskah Publikasi) Naskah Publikasi revisi 1.pdf Download (1MB)

Abstract

Inflammation is the body's defense response to physical, chemical and mechanical stimuli. The galangal rhizome (Alpinia galanga) is used as an anti-inflammation empirically. The objective of this research was to determine the antiinflammatory activity of galanga rhizome extract in white male rats wistar strain induced by 1% carragenin. The extraction of galanga rhizome was done by using maceration in ethanol 96%. Zerumbon content in the extract was known by qualitative test with TLC. A total of 12 rats were divided into four groups. Group I (negative control) was treated with 0.5% CMC-Na, group II (positive control) was given with 10 mg/kgBB dose of Diclofenac, and groups III and IV were treated with ethanol extract of galangal rhizome with doses of 200 and 500 mg/kg body weight. The observation was performed for 7 hours with frequency measurement of oedem volume every 30 minutes. Data obtained from udem volume measurements were used to calculate AUC (Area Under the Curve) and percent anti-inflammatory power. The data were then analyzed by Kruskal-Wallis and continued by Moses extreme reaction test. Result showed that 200 and 500 mg/kg body weight of ethanol extract of galangal rhizome has antiinflammatory effect on Wistar strain white male rat 31,22% and 18,49%, respectively.

Item Type:	Karya ilmiah (Skripsi)
Uncontrolled Keywords:	antiinflammatory, ethanol extract, galangal rhizome (Alpinia galanga), karagenin
Subjects:	R Medicine > R Medicine (General)
Divisions:	Fakultas Farmasi > Farmasi
Depositing User:	Intan Arsyita Sari
Date Deposited:	06 Feb 2018 08:08
Last Modified:	06 Feb 2018 08:08
URI:	http://eprints.ums.ac.id/id/eprint/59393

Actions (login required)

View Item