Analisis Efektivitas - Biaya Pemberian Antibiotik Sefotaksim Dan Seftriakson Untuk Diare Akut Akibat Infeksi Pada Pasien Anak Yang Menjalani Rawat Inap Di Rumah Sakit

Rahardjoputro, Rolando and ., Tri Murti Andayani, Sp.FRS., PhD., Apt (2020) Analisis Efektivitas - Biaya Pemberian Antibiotik Sefotaksim Dan Seftriakson Untuk Diare Akut Akibat Infeksi Pada Pasien Anak Yang Menjalani Rawat Inap Di Rumah Sakit. Thesis thesis, Universitas Muhammadiyah Surakarta.

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Abstract

Antibiotic administration is one of the important therapies in cases of acute infectious diarrhea in pediatric so that the cost-effectiveness of antibiotics is taken into account in a therapy. Ceftriaxone is recommended in several guidelines for the treatment of infectious diarrhea while cefotaxime has not been widely recommended even though it is known to be evidence-based to be more cost effective than ceftriaxone. The purpose of this study was to determine the comparison of effectiveness, cost of therapy and antibiotic that is more cost effective for the treatment of acute infectious diarrhea between cefotaxime and ceftriaxone antibiotics in pediatric patients who are hospitalized. This study uses the perspective of a health service provider, which is the hospitals. This study was conducted in a multicenter retrospective cohort by taking patient data from January 2019 to January 2020. The research data includes medical records and patient care bill. Analysis of research data using a decision tree to determine the average cost of an antibiotic therapy and the value of the Cost Effectiveness Ratio. A total of 50 pediatric patients met the inclusion criteria in this study consisting of 21 patients in the cefotaxime group and 29 patients in the ceftriaxone group. The effectiveness of antibiotics using success rate parameters and the incidence of side effects showed a higher effectiveness of cefotaxime (85.7%) than ceftriaxone (79.4%). The average cost of using cefotaxime antibiotics was Rp.1.418.443 and ceftriaxone was Rp.1.473.779. The ICER value for cefotaxime and ceftriaxone was Rp.-878.349. This study concluded that the use of cefotaxime antibiotic has higher effectiveness and lower average cost than ceftriaxone antibiotic and is more cost effective for the treatment of acute diarrhea due to infection in pediatric patients who are hospitalized.

Item Type: Karya ilmiah (Thesis)
Uncontrolled Keywords: Analisis Efektivitas Biaya, Sefotaksim, Seftriakson, Diare Akut Infeksi, Pasien Anak
Subjects: R Medicine > RJ Pediatrics > RJ101 Child Health. Child health services
R Medicine > RM Therapeutics. Pharmacology
R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Pasca Sarjana > Magister Farmasi
Depositing User: ROLANDO RAHARDJOPUTRO
Date Deposited: 21 Nov 2020 04:10
Last Modified: 21 Nov 2020 04:11
URI: http://eprints.ums.ac.id/id/eprint/87659

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