Wardhani, Amallia Kusuma and -, Prof. Dr. dr. EM Sutrisna, M.Kes. (2019) Evaluasi Drug Related Problems (DRPS) Kategori Pemilihan Dosis, Kontraindikasi Dan Interaksi Obat Pada Kemoterapi Kanker Kolorektal Di Instalasi Rawat Inap RSUD Dr. Moewardi Tahun 2018. Skripsi thesis, Universitas Muhammadiyah Surakarta.
![[img]](http://eprints.ums.ac.id/style/images/fileicons/application_pdf.png) |
PDF (Naskah Publikasi)
Naskah Publikasi PERPUS FIX.pdf Download (1MB) |
|
PDF (Lampiran)
LAMPIRAN.pdf Restricted to Repository staff only Download (283kB) | Request a copy |
|
PDF (Surat Pernyataan Publikasi Ilmiah)
Surat Pernyataan Publikasi Ilmiah.pdf Restricted to Repository staff only Download (255kB) | Request a copy |
Abstract
Colorectal cancer is a malignancy that occurs in the colon or rectum and most often occurs third in the world. Drug Related Problems (DRPs) are drug-related problems that can interfere with the desired therapeutic effects and affect the safety and effectiveness of these therapies. Many chemotherapy regimens that patient receive can lead to occurance of DRPs, therefore evaluation of DRPs is one of important thing for this study. The purpose of this study was to determine the incidence of DRPs in the selection of doses, contraindications and drug interactions in colorectal cancer chemotherapy at the inpatient care Dr. Moewardi in 2018. This study was non-experimental with retrospective data collection using patient medical record data and analyzed descriptively, using inclusion criteria, namely patients diagnosed with colon or rectal cancer, having identity patient and complete drug data, having SGOT, SGPT and SCr laboratory data. The guideline of this study is Panduan Nasional Pelayanan Kanker (PNPK) Colorectal Cancer in 2018, Drug Information Handbook 17th Edition 2009, Medscape Drug Interaction Checker Online, Drugs.com and Stockley’s Drug Interaction 8th Edition. The results of the study showed that as many as 23 patients with 109 cases of colon cancer and rectal cancer 24 patients with 97 cases were included in the inclusion criteria. These cases consisting of colon cancer in 31 cases of drug dose too low (30.40%) and 1 case of dose too high (1%), 8 cases of contraindications (7.74%) and 63 cases of drug interactions (61.76%). Rectal cancer in 28 cases of drug dose too low (28.87%) and drug dose too high 1 case (1,03%), 7 cases of contraindications (7.22%) and 61 cases of drug interactions (62.88%).
| Item Type: | Karya ilmiah (Skripsi) |
|---|---|
| Uncontrolled Keywords: | colorectal cancer, DRPs, dose selection, contraindicate, interaction. |
| Subjects: | R Medicine > RS Pharmacy and materia medica |
| Divisions: | Fakultas Farmasi > Farmasi |
| Depositing User: | AMALLIA KUSUMA WARDHANI |
| Date Deposited: | 13 Aug 2019 07:38 |
| Last Modified: | 13 Aug 2019 07:40 |
| URI: | http://eprints.ums.ac.id/id/eprint/75966 |
Actions (login required)
 |
View Item |
