Uji Efek Analgesik Ekstrak Methanol Kulit Pisang Kepok (Musa paradisiaca) pada Mencit (Mus musculus) Putih Jantan Galur Swiss

Syachriani, Mien Alvinna and , Dr. Devi Usdiana Rosyidah, M.Sc. (2018) Uji Efek Analgesik Ekstrak Methanol Kulit Pisang Kepok (Musa paradisiaca) pada Mencit (Mus musculus) Putih Jantan Galur Swiss. Skripsi thesis, Universitas Muhammadiyah Surakarta.

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Abstract

Background: Banana or Musa paradisiaca (commonly called pisang kepok in Indonesian) is one of the most cultivated fruit. Till date, the stem and the leaves of banana fruit have been proven to have analgesic effect. However, there is no study for analgesic effect of banana peel. Flavonoid which contained in banana peel is thought to be responsible for the analgesic effect of the fruit. Objective: To study the analgesic effect of methanolic extract of banana (Musa paradisiaca) peel. Method: The method used in this research was post test only with controlled group design. The laboratory animals used were 30 Swiss strain male albino mice (Mus musculus) which divided into 5 treatment groups; group I as negative control group given aquadest, group II as positive control group given Ibuprofen with dose 450 mg/kgBW, group III as the treatment group I given EMKP dose 500 mg/kgBW, group IV as treatment group II given EMKP dose 1000 mg/kgBW, group V as treatment group III given EMKP dose 1,500 mg/kgBW. Results: Based on the result of Kruskal-Wallis statistic test, p = 0,000, which means p < 0,05 significant. Mann-Whitney test results obtained between negative control group and treatment group 1, 2 and 3; p = 0,000; p = 0,000; p = 0.000 (p < 0.05) which mean the results are significantly different. Conclusion: Methanolic extract of banana (Musa paradisiaca) peel has an analgesic effect on Swiss strain male albino mice (Mus musculus).

Item Type:	Karya ilmiah (Skripsi)
Uncontrolled Keywords:	ekstrak kulit pisang kepok, Musa paradisiaca, analgesik
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Fakultas Kedokteran > Kedokteran
Depositing User:	MIEN ALVINNA SYACHRIANI
Date Deposited:	02 Feb 2018 01:53
Last Modified:	02 Feb 2018 01:53
URI:	http://eprints.ums.ac.id/id/eprint/58940

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