Uji Efektivitas Antibakteri Minyak Atsiri Daun Sirih Merah (Piper Crocatum Ruiz & Pav.) Terhadap Staphylococcus epidermidis secara In Vitro

Bramantio, Richard Guntur and , Dr. Devi Usdiana Rosyidah, M. Sc (2018) Uji Efektivitas Antibakteri Minyak Atsiri Daun Sirih Merah (Piper Crocatum Ruiz & Pav.) Terhadap Staphylococcus epidermidis secara In Vitro. Skripsi thesis, Universitas Muhammadiyah Surakarta.

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Abstract

Background: Red betel leaves (Piper crocatum Ruiz & Pav) was one of Indonesian traditional medicinal plants that had many benefits and one of them as antibacterial. One of the content in red betel leaves was essential oil that had the ability as an antibacterial. The mechanism of essential oil of red betel leaves in inhibiting bacterial growth was disturbing the integrity of the cell membrane. Objective: To determine the effectiveness of antibacterial essential oils of red betel leaves (Piper crocatum Ruiz & Pav) against Staphylococcus epidermidis in vitro. Method: Type of experimental research with post test method only with control group design. The bacteria used were Staphylococcus epidermidis in nutrient agar media. Each bacteria received seven different treatments such as essential oil concentration 5%, 10%, 20%, 40%, 80%, positive control, and negative control. The positive control usedwas clindamycin solution. Antibacterial test used diffusion method with well technique. Result: Based on Kruskal-Wallis test results obtained p value of 0,000 which meant there were significant differences in antibacterial activity. In the Mann-Whitney test results, all concentrations of essential oils were significantly different from the negative controls, except for the 5% concentration. When compared with positive control, all concentrations had significant differences. On Spearman test results obtained p value 0.002 and correlation coefficient was 0.552 which meant a significant correlation between variables associated with the level correlation was medium. Conclusion: The essential oil of red betel (Piper crocatum Ruiz & Pav.) had antibacterial properties against Staphylococcus epidermidis.

Item Type:	Karya ilmiah (Skripsi)
Uncontrolled Keywords:	antibakteri, minyak atsiri, Piper crocatum Ruiz & Pav.
Subjects:	R Medicine > RS Pharmacy and materia medica R Medicine > RZ Other systems of medicine
Divisions:	Fakultas Kedokteran > Kedokteran
Depositing User:	RICHARD GUNTUR BRAMANTIO
Date Deposited:	22 Jan 2018 02:23
Last Modified:	22 Jan 2018 02:23
URI:	http://eprints.ums.ac.id/id/eprint/58368

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