Efektivitas Uji Daya Antibakteri Bentonit Terhadap Bakteri Pseudomonas Aeruginosa Secara In Vitro

Prihandaru, Pramudya Raditya and , drg. Dendy Murdiyanto, MDSc (2022) Efektivitas Uji Daya Antibakteri Bentonit Terhadap Bakteri Pseudomonas Aeruginosa Secara In Vitro. Skripsi thesis, Universitas Muhammadiyah Surakarta.

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Abstract

Periodontitis is a chronic inflammatory disease whose main etiology is pathogenic bacteria in dental plaque. One of the bacterial species that is often involved is the gram-negative bacterium Pseudomonas aeruginosa. Treatment of periodontitis by eliminating periodontal pathogens using conventional antibiotic agents is currently facing limitations related to the development of Multi Drug Resistant. Certain natural clay minerals have been identified as having the ability to kill pathogenic bacteria. Bentonite is a natural clay with montmorillonite as the main component. Montmorillonite has a layered structure and the surface is negatively charged with ions in the interlayer space. These ions are exchangeable allowing the free exchange of positively charged ions, such as metal cations. These metal cations are responsible for the antibacterial activity of the clay. Research Objectives: This study aims to determine the antibacterial power of bentonite against the growth of Pseudomonas aeruginosa bacteria in vitro. Method: This type of research is True Experimental Laboratories with Posttest Only Control Group Design. The study used 7 sample groups, namely 5 bentonite treatment groups with concentrations of 5%, 10%, 20%, 40% and 100%, as well as 2 control groups, positive control of ciprofloxacin and negative control of distilled water. Each group was replicated 4 times, so there were a total of 28 samples. Results: The results showed that only the positive control group showed an inhibition zone, while the bentonite sample group with concentrations of 5%, 10%, 20%, 40% and 100% and the negative control group did not show an inhibition zone on the growth of Pseudomonas aeruginosa. Conclusion: Bentonite has no antibacterial activity against Pseudomonas aeruginosa in vitro.

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	bentonite, antibacterial, Pseudomonas aeruginosa
Subjects:	R Medicine > R Medicine (General)
Divisions:	Fakultas Kedokteran Gigi > Kedokteran Gigi
Depositing User:	PRAMUDYA RADITYA PRIHANDARU
Date Deposited:	22 Nov 2022 03:43
Last Modified:	22 Nov 2022 03:44
URI:	http://eprints.ums.ac.id/id/eprint/106161

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