Artikel Review : Sitotoksisitas Ekstrak Etanol Daun Mangrove (Rhizophora) Terhadap Sel Kanker

SAPUTRI, NUR FAJARIYAH MAULIDAH and , Dr. Haryoto, M.Sc. (2021) Artikel Review : Sitotoksisitas Ekstrak Etanol Daun Mangrove (Rhizophora) Terhadap Sel Kanker. Skripsi thesis, Universitas Muhammadiyah Surakarta.

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Cancer is a disease that can attack any part of the body when the abnormal cells begin to grow uncontrollably beyond the limit, then attack the connected parts of the body and / or spread to other organs. The mangrove (Rhizophora) is a herbal plant that can be used as a treatment for various diseases, one of which is cancer. The mangrove (Rhizophora) plant contains phytochemicals ranging from fruit, seeds, leaves and roots. This review article aims to examine the cytotoxicity effects of mangrove (Rhizophora) plants on cancer cells. The library sources in this article review use the Google Scholar and PubMed databases. The inclusion criteria used were articles containing the cytotoxic test of mangrove (Rhizophora) with the last 10 years of publication (2011-2020), original research, there were results of anticancer activity in the form of IC50 and research using mangrove (Rhizophora). plant extracts The exclusion criteria used were articles that did not contain a full text, used plants with different genus, did not have an IC50 value and were not original research. From the journals that have been analyzed, it can be said that the extract of the mangrove (Rhizophora) plant can be developed for cancer treatment. mangrove (Rhizophora) plant has cytotoxic activity because it contains active compounds in the form of phenolic, flavonoids and terpenoids. Based on the results of the cytotoxic test of mangrove (Rhizophora) extract, the plant parts that have the strongest cytotoxic effect are fruit.

Item Type: Karya ilmiah (Skripsi)
Uncontrolled Keywords: Cytotoxic, Rhizophora, MCF-7, IC50.
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Farmasi
Date Deposited: 14 Aug 2021 07:31
Last Modified: 14 Aug 2021 07:31

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