Uji Aktivitas Diuretik Ekstrak Etanol 96% Daun Kelor (Moringa oleifera) Pada Tikus Galur Wistar Jantan

Cahyadi, Dody Dwi and -, Tanti Azizah Sujono, M.Sc., Apt (2018) Uji Aktivitas Diuretik Ekstrak Etanol 96% Daun Kelor (Moringa oleifera) Pada Tikus Galur Wistar Jantan. Skripsi thesis, Universitas Muhammadiyah Surakarta.

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Moringa oleifera is one of the plants known to have diuretic effect from previous research. Leaves contain flavonoid compounds that can have an effect to shed urine. This study aimed to test the effect of diuretic ethanol extract of Moringa leaf. A total of 35 rats were divided into 7 groups consisting of negative control group (CMC Na 0.5%), Standard I (Furosemid), Standard II (urea), and ethanol extract of moringa leaf dose 50 mg / kgBW, 100 mg / kgBW, 200 mg / kgBW, and 400 mg / kgBW. Treatment of each group as much as 5 mL / kgBW and given 0.9% NaCl 5 mL / kgBW, then put in a metabolic cage. Based on cumulative urine volume for 5 hours and 24 hours calculated Lipschitz value, AUC (Area Under Curve) was tested statistically with Kruskal-Wallis continued by MannWhitney with 95% confidence level. Leaf ethanol extract of dose 400 mg / kgBW able to give effect of diuretic at 1-5 and 1-24 hours with Lipschitz value 1,31 and 1,11. Leaf ethanol extract of dose 50, 100, 200 mg / kgBW had not shown any diuretic effect.

Item Type: Karya ilmiah (Skripsi)
Uncontrolled Keywords: Moringa leaf extract, Moringa oleifera, lipschitz, diuretic.
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Farmasi
Depositing User: DODY DWI CAHYADI
Date Deposited: 01 Aug 2018 02:24
Last Modified: 01 Aug 2018 02:25
URI: http://eprints.ums.ac.id/id/eprint/64567

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