Rosita, Safira Sarah and , Azis Saifudin, Ph.D., Apt. (2017) Uji Sitotoksisitas Ekstak Metanol Jamur Dari Isolat Tanah Di Daerah Istimewa Yogyakarta Terhadap Sel Kanker Payudara MCF7. Skripsi thesis, Universitas Muhammadiyah Surakarta.
PDF (Naskah Publikasi)
NASKAH PUBLIKASI.pdf Download (1MB) |
|
PDF (Halaman Depan)
HALAMAN DEPAN.pdf Download (1MB) |
|
PDF (Bab I)
BAB I.pdf Download (166kB) |
|
PDF (Bab II)
BAB II.pdf Restricted to Repository staff only Download (186kB) | Request a copy |
|
PDF (Bab III)
BAB III.pdf Restricted to Repository staff only Download (594kB) | Request a copy |
|
PDF (Bab IV)
BAB IV.pdf Restricted to Repository staff only Download (71kB) | Request a copy |
|
PDF (Daftar Pustaka)
DAFTAR PUSTAKA.pdf Download (94kB) |
|
PDF (Lampiran)
LAMPIRAN.pdf Restricted to Repository staff only Download (683kB) | Request a copy |
|
PDF (Pernyataan Publikasi Ilmiah)
Pernyataan Publikasi Ilmiah.pdf Restricted to Repository staff only Download (481kB) | Request a copy |
Abstract
Soil is a media of growth and development the variety of microorganism. This study aim to explore the fungal of five soil samples in the different ecosystem such as coast, salak plantation, volcano slope, fields, and disposal of cow wasting against the cytotoxic effects of breast MCF 7 cancer cell line. Soil sample was cultured and growing of fungal identified macroscopically. The extraction of fungal sample and Czapek dox media used methanol. Cytotoxic test with MTT assay method was done against breast MCF 7 cancer cell line with variants sample concentration 500; 250; 125; 62,5; 31,25 μg/mL. Qualitative test was carried out on samples that have IC50 with stationary phase silica plate GF254 and mobile phase n-hexane : ethyl acetate (1:3). The result of cytotoxic test showed extract methanol of fungal coast had IC50 values 140 μg/mL, the other four extract methanol of fungal increased cell live in MCF 7 cell line. Qualitative test was carried out on extract methanol of fungal coast, showed the separation of components that were not owned Czapek dox media. So that inferential the extract methanol of fungal coast has an inhibitory effect on the growth of MCF 7 cells, the other four extract methanol of fungal has no cytotoxic effects on MCF 7 cells. Qualitative test is known that extract methanol of fungal coast has varying component.
Item Type: | Karya ilmiah (Skripsi) |
---|---|
Uncontrolled Keywords: | Jamur tanah, sitotoksik, sel MCF 7 |
Subjects: | Q Science > QH Natural history > QH301 Biology |
Divisions: | Fakultas Farmasi > Farmasi |
Depositing User: | SAFIRA SARAH ROSITA |
Date Deposited: | 04 Feb 2017 01:51 |
Last Modified: | 04 Feb 2017 01:51 |
URI: | http://eprints.ums.ac.id/id/eprint/48950 |
Actions (login required)
View Item |