Tandari, Anita Dwi and , Prof. Dr. M Kuswandi, SU., M.Phil., Apt. and , Ratna Yuliani, M.Biotech.St. (2016) Pola Resistensi Bakteri terhadap Antibiotik pada Penderita Infeksi Saluran Kemih (ISK) di RSUP Dr. Soeradji Tirtonegoro Klaten Periode Januari 2013-September 2015. Skripsi thesis, Universitas Muhammadiyah Surakarta.
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Abstract
Urinary tract infection (UTI) is a state of inflammation in the urothelium cells lining urinary tract. The incidence of urinary tract infections in the Hospital Dr. Soeradji Tirtonegoro Klaten 2014 is the highest nosocomial infection followed by infection Deku (dekubitis), IADP (Peripheral Blood Stream Infection), VAP (Ventilatory Acquired Pneumonia), ILO (Wound Infection Operation). Urinary tract infection patients is most prevalent more than 60 years because in women aged 18-40 years were found asymptomatic bacteria (5-6%) and increased in the elderly (20%). Treatment of patients with infections usually with antibiotics. Treatment with antibiotics should be rational because irrational use of antibiotics will cause unwanted side effects and increasing bacterial resistance. The aim of this research is to find out the bacteria that cause of UTI, the patterns of bacterial resistance and the appropriateness of using antibiotics based on sensitivity test results and the spectrum of antibiotic activity at RSUP Dr. Soeradji Tirtonegoro Klaten during January 2013-September 2015. This research was carried out by collecting data retrospectively and the data were analyzed descriptively. A total of 25 UTI patients have data UTI definitive antibiotics from bacterial culture test results and sensitivity test of bacteria antibiotics. The data were analyzed to find out the causes UTI and patterns of bacterial resistance to antibiotics and the appropriateness of using antibiotics based on the results of bacterial culture, bacterial sensitivity test and the spectrum of antibiotic activity. A total of 15 types of bacteria cause UTI were identified form 25 urine samples of UTI patients. Pseudomonas sp. and Enterococcus sp. were bacteria that causes most UTIs (17.85%), followed by Escherichia coli (10.71%). Pseudomonas sp. resistant to ceftriaxone and cefixime (100%), ampicillin, tetracycline, levofloxacin, and ciprofloxacin respectively (80%) and gentamicin (20%). Escherichia coli resistant to ceftriaxone and cefixime (66.6%) and tetracycline (33.3%). Enterococcus sp. resistant to ceftriaxone, cefixime, levofloxacin respectively by 100%, gentamicin, tetracycline, and ciprofloxacin (80%). Thirty percent of antibiotics definitive which were given to UTI patients were appropriate with the results of bacterial culture, bacterial sensitivity test, and the spectrum of antibiotic activity.
| Item Type: | Karya ilmiah (Skripsi) |
|---|---|
| Uncontrolled Keywords: | Resistance, antibiotic, urinary tract infections. |
| Subjects: | R Medicine > RM Therapeutics. Pharmacology R Medicine > RS Pharmacy and materia medica |
| Divisions: | Fakultas Farmasi > Farmasi |
| Depositing User: | ANITA DWI TANDARI |
| Date Deposited: | 23 Jun 2016 03:29 |
| Last Modified: | 23 Jun 2016 03:29 |
| URI: | http://eprints.ums.ac.id/id/eprint/44216 |
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