Formulasi Sediaan Gel Basis Na-Cmc Ekstrak Etanol Daun Cocor Bebek (Kalanchoe Pinnata (Lmk.) Pers.) Sebagai Penyembuh Luka Bakar Pada Kelinci

Istiana, Sarah and , Tanti Azizah S, M.Sc.,Apt and , Suprapto, M.Sc., Apt (2016) Formulasi Sediaan Gel Basis Na-Cmc Ekstrak Etanol Daun Cocor Bebek (Kalanchoe Pinnata (Lmk.) Pers.) Sebagai Penyembuh Luka Bakar Pada Kelinci. Skripsi thesis, Universitas Muhammadiyah Surakarta.

	PDF (NASKAH PUBLIKASI) NASKAH PUBLIKASI.pdf Download (490kB)
	PDF (Halaman Depan) COVER+HALAMAN DEPAN.pdf Download (251kB)
	PDF (Bab I) BAB 1.pdf Download (55kB)
	PDF (Bab II) BAB 2.pdf Restricted to Repository staff only Download (72kB) | Request a copy
	PDF (Bab III) BAB 3.pdf Restricted to Repository staff only Download (239kB) | Request a copy
	PDF (Bab IV) BAB 4.pdf Restricted to Repository staff only Download (25kB) | Request a copy
	PDF (Daftar Pustaka) DAFTAR PUSTAKA.pdf Download (33kB)
	PDF (Lampiran) LAMPIRAN.pdf Restricted to Repository staff only Download (454kB) | Request a copy
	PDF (Pernyataan Publikasi Ilmiah) SURAT PERNYATAAN PUBLIKASI.pdf Restricted to Repository staff only Download (548kB) | Request a copy

Abstract

The compounds flavonoid, bufadienolides, saponin in the Kalanchoe pinnata have function to cure burns is the flavonoid. The mechanism of action flavonoid and bufadienolides as anti-bacterial with protein denature bacterial cell. Saponin mechanism by increasing collagen formation, so that wound be quickly healed. This study was aimed to determine the effectiveness of the ethanol extract of Kalanchoe pinnata gel to cure burns and to determine the concentration level of the ethanol extract of Kalanchoe pinnata gel to cure burn. The extraction of Kalanchoe pinnata was done by using ethanol 96% with maceration method. The rendemen result of Kalanchoe pinnata extract is 2,13%. The gel Na-CMC basis was made into 4 formulas, they are: gel without extract (F1), 1% gel (F2), 2.5% (F3) and 5% (F4). Gel evaluated the physical characteristic such as organoleptic, homogeneity, pH, viscosity, and dispersive power. The animal used for test were 6 Australian rabbits. The back skin of the rabbits was shaven then anaesthetized by using ethyl chloride spray, after that the inducers tool heated for 1 minutes was put on the skin for 5 second in a diameter of 2 cm. The result of the research showed that the ethanol extract of Kalanchoe pinnata gel did not have effect 0,332 (p> 0.05). Keywords: Kalanchoe pinnata, burns, Na-CMC

Item Type:	Karya ilmiah (Skripsi)
Uncontrolled Keywords:	Data, Informasi, Perpustakaan
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Fakultas Farmasi > Farmasi
Depositing User:	SARAH ISTIANA
Date Deposited:	21 Jun 2016 06:48
Last Modified:	21 Jun 2016 06:48
URI:	http://eprints.ums.ac.id/id/eprint/44201

Actions (login required)

View Item