Uji Efek Hepatorepair Ekstrak Temulawak (Curcuma Xanthorrhiza Roxb) Pada Tikus Putih Jantan Galur Wistar Yang Diinduksi Paracetamol

HADINATA, MUHAMMAD TEGUH and , dr. Nurhayani M.Sc and , dr. Rochmadina Suci Bestari M.Sc (2016) Uji Efek Hepatorepair Ekstrak Temulawak (Curcuma Xanthorrhiza Roxb) Pada Tikus Putih Jantan Galur Wistar Yang Diinduksi Paracetamol. Skripsi thesis, Universitas Muhammadiyah Surakarta.

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Abstract

Background: Temulawak (Curcuma xanthorrhiza Roxb) compounds curcumin, essential oil, glycosides, toluil, protein, and calium. Curcumin has the effect hepatorepair. This research use ginger rhizome. Ginger rhizome serves as hepatorepair. Objective: This study aimed to find out hepatorepair effect of Temulawak (Curcuma xanthorrhiza Roxb) on male wistar strain rats induced by paracetamol. Methods: The method was experimental research with pre and postest control group design. Treatment group I was given distilled water (aquadest) as negative control, group II was given paracetamol as positive control, group III was given of ginger extract at a dose of 400 mg/kgBB, group IV was given of ginger extract at a dose of 800 mg/kgBB, group V was given of ginger extract at a dose of 1600 mg/kgBB. Result: ANNOVA test p value 0,000 for SGOT, and 0,002 for SGPT. It means that these two value <0,05 which can be interpreted to have the effect of ginger extract hepatorepair with the result obtained in the ANNOVA test. Conclusion: Ginger extract (Curcuma xanthorrhiza Roxb) had hepatorepair effect on male wistar strain rats induced by paracetamol.

Item Type:	Karya ilmiah (Skripsi)
Uncontrolled Keywords:	Temulawak, Hepatorepair, Rattus norvegicus
Subjects:	R Medicine > RM Therapeutics. Pharmacology
Divisions:	Fakultas Kedokteran
Depositing User:	MUHAMMAD TEGUH HADINATA
Date Deposited:	20 Apr 2016 05:03
Last Modified:	20 Apr 2016 05:04
URI:	http://eprints.ums.ac.id/id/eprint/42454

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