Pengaruh Propoelixtm Terhadap Kadar Ureum Serum Tikus Jantan Strain Wistar Albino Model Gagal Ginjal Kronik Induksi Acetaminophen

Maulana, Ria Sukma and , dr. Listiana Dharmawati Suryaningrum, S.Ked., M.Si (2021) Pengaruh Propoelixtm Terhadap Kadar Ureum Serum Tikus Jantan Strain Wistar Albino Model Gagal Ginjal Kronik Induksi Acetaminophen. Skripsi thesis, Universitas Muhammadiyah Surakarta.

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Abstract

This study aimed to determine the effect of propoelix™ on serum urea levels of male rats wistar albino strain CKD models induced by acetaminophen. This study is true experimental design with pre-test – post-test on male rats of wistar albino strain. The samples were 28 rats which were divided into 4 groups, G1 (negative control group/non-CKD), G2 (positive control group/CKD), G3 (treatment group propoelix™ dose 0,0216g/200g BW/day), and G4 (treatment group propoelix™ dose of 0,0432g/200g BW/day). G2, G3, and G4 induced by acetaminophen dose 1g/kg BW for 14 days. Measurement of serum urea levels was carried out by the enzymatic method. Data analysis was carried out with the One Way Anova test. The results showed a significant decrease (p<0,01) in delta serum urea of rats. There was a decrease in serum urea by 2 times in treatment group propoelix™ dose of 0,0216g/200g BW/day and almost 3 times in treatment group propoelix™ dose of 0,0432g/200g BW/day.

Item Type: Thesis (Skripsi)
Uncontrolled Keywords: Gagal Ginjal, Propoelix, Ureum Serum
Subjects: R Medicine > R Medicine (General)
Divisions: Fakultas Ilmu Kesehatan > Gizi
Depositing User: RIA SUKMA MAULANA
Date Deposited: 27 Dec 2021 04:07
Last Modified: 27 Dec 2021 04:07
URI: http://eprints.ums.ac.id/id/eprint/96255

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