Analisis Drug Related Problems Terkait Dengan Ketidaktepatan Dosis Dan Interaksi Obat Pada Pasien Penyakit Paru Obstruksi Kronik (PPOK) Di RSUD DR. Moewardi Tahun 2015

Priastuti, Nisrina Fauzany and , Hidayah Karuniawati, M.Sc., Apt (2017) Analisis Drug Related Problems Terkait Dengan Ketidaktepatan Dosis Dan Interaksi Obat Pada Pasien Penyakit Paru Obstruksi Kronik (PPOK) Di RSUD DR. Moewardi Tahun 2015. Skripsi thesis, Universitas Muhammadiyah Surakarta.

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Abstract

Chronic obstructive pulmonary disease (COPD) is a chronic respiratory disorder that the incidence is increasing year by year. It is important to monitor the treatment of COPD in order to achieve optimal therapy. This study aims to determine the description and analyze the incidence of DRPs associated with the inaccuracy of dosage and drug interactions in patients with COPD in Dr. Moewardi Hospital in 2015. This research was non experimental research with retrospective retrieval data which was analyzed descriptively. Samples were collected with purposive sampling method. The inclusion criteria for this study were patients diagnosed with COPD, getting 2 or more of the drugs used together, and having complete medical record data. Data analysis of dosage inaccuracy was evaluated using British National Formulary Edition 61 2011, Drug Information Handbook 17th, Informatorium Obat Nasional Indonesia 2008. Analysis of potential drug interactions was evaluated using Stockley's Drug Interaction in 2008 and drug interaction checker www.drugs.com/druginteractions.html. Based on the results of the study, 40 medical records of patients with DRP incidence were 30 (75%) and those without DRPs were 10 patients (25%). The dosage incompatibility category had 9 patients (10%) consisting of 2 patients (5%) getting high dose and 8 patients (20%) getting low dose. While for drug interaction event category there were 30 patients (75%) 0f 85 cases, covering major severity were 21 cases (24,7%), moderate counted 56 cases (65,9%), and minor were 8 cases (19,4% ).

Item Type: Karya ilmiah (Skripsi)
Uncontrolled Keywords: DRPs, high dose, low dose, drug interactions, COPD
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Farmasi
Depositing User: NISRINA FAUZANY PRIASTUTI
Date Deposited: 14 Aug 2017 07:24
Last Modified: 14 Aug 2017 07:24
URI: http://eprints.ums.ac.id/id/eprint/55439

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