Mahendra, Wahyudi Rizki and , Ambar Yunita Nugraheni, M.Sc.,Apt (2022) Drug Related Problems Pada Pasien Tuberkulosis Paru Kategori 1 Di Instalasi Rawat Jalan Rsup Dr. Soeradji Tirtonegoro Klaten Tahun 2020. Skripsi thesis, Universitas Muhammadiyah Surakarta.
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Abstract
TB patients require a lot of drugs for their disease, thus increasing the possibility of Drug Related Problems (DRPs). The purpose of this study was to evaluate DRPs in the category of drug inaccuracy (ineffective/non-drug of choice, contraindications), dose inaccuracy (under dose, over dose) and drug interactions that occur in category 1 pulmonary TB patients at the Outpatient Installation of dr. Soeradji Tirtonegoro Klaten 2020. This research is a non-experimental (observational) study with retrospective data collection. The population taken includes TB patients who visit the outpatient installation of dr. Soeradji Tirtonegoro Klaten in 2020. The data were taken from the medical records of category 1 TB patients at the outpatient installation of dr. Soeradji Tirtonegoro Klaten. The data were analyzed descriptively based on the 2014 Pulmonary Tuberculosis Control Guidelines 2nd edition to evaluate the accuracy of drugs and doses on OAT while the Drug Information Handbook 25 of 2017 for other drugs received by patients. Stokley's Drug Interaction Eight Edition 2008, Drug Interaction Fact, and Drug Interaction Checker (www.drugs.com) to analyze interactions that occur between OAT and other drugs. The results of the analysis of patient data, found 98 total visits/prescribing of 13 category 1 pulmonary TB patients in the outpatient installation of dr. Soeradji Tirtonegoro Klaten in 2020 according to the inclusion criteria. The results of the evaluation of DRPs, found that 98 correct drug prescriptions were found but found that DRPs in the subdose category were 63 cases (64.28%) and 11 cases (11.22%) had DRPs in the over-dose category and 14 cases were prescribed (14.28%) experienced the incidence of DRPs. drug interactions. Major interaction was 1 case (1.02%), moderate interaction was 9 cases (9.18%) and minor interaction was 4 cases (4.08%). Pharmacodynamic interaction in 1 case (1.02%) and pharmacokinetic interaction in absorption phase in 3 cases (3.06%), metabolism in 9 cases (9.18%).
| Item Type: | Thesis (Skripsi) |
|---|---|
| Additional Information: | Tidak Publikasi karena akan diterbitkan di Jurnal lain |
| Uncontrolled Keywords: | drug related problems, Tuberculosis, TB category 1. |
| Subjects: | R Medicine > RS Pharmacy and materia medica |
| Divisions: | Fakultas Farmasi > Farmasi |
| Depositing User: | WAHYUDI RIZKI MAHENDRA |
| Date Deposited: | 09 Aug 2022 02:38 |
| Last Modified: | 09 Aug 2022 02:43 |
| URI: | http://eprints.ums.ac.id/id/eprint/103177 |
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